Oregon Ducks vs Ohio State Buckeyes Predictions
Saturday, November 7, 2026 at 3:30pm EST at Ohio Stadium, Columbus, OH
Buckeyes
Professional Picks On This Game
Oregon Ducks vs. Ohio State Buckeyes Prediction: Price Makes Ohio State a Pass
Analysis updated November 7, 2026 at 8:50 AM CST
Ohio State is the likely winner, but neither the -305 moneyline nor the -7.5 spread is supported well enough to bet.
Ohio State's availability picture
The Columbus Dispatch via Yahoo Sports reports that Ohio State receivers Brandon Inniss and Brock Boyd are doubtful against Oregon. Their possible absences add risk to backing the Buckeyes as 7.5-point favorites.
Left tackle Ian Moore was removed from the availability report after initially being listed as questionable. His expected availability helps Ohio State's offensive line, but it doesn't resolve the uncertainty at receiver.
Betting outlook
SPF lists Ohio State at -305 on the moneyline and Oregon at +245. That price makes the Buckeyes the likely winner, but the available evidence doesn't include current records, recent results, season statistics or confirmed starters. Those gaps make -305 too expensive and leave too little support for laying 7.5 points.
The total is 45.5, with the over at -105 and the under at -115. Without team performance, pace or weather data, there isn't a sound basis for either side of the total. Pass on the moneyline, spread and total.