NCAAF Predictions

USC Trojans vs Rutgers Scarlet Knights Predictions

Saturday, September 19, 2026 at 3:30pm EST at SHI Stadium, Piscataway, NJ

USC

Trojans

3-0
Spread -21.5
@
Rutgers

Scarlet Knights

0-2
Spread +21.5
50% 50%
Spread USC Trojans -21.5 Rutgers Scarlet Knights +21.5
Moneyline USC Trojans -2100 Rutgers Scarlet Knights +1100
Total Over 58.5 (-102) Under 58.5 (-118)

Who wins this game?

Professional Picks

Professional Picks On This Game

6 available
Staff Preview

USC vs. Rutgers Prediction: Quarterback Questions Matter at -21.5

Analysis updated September 18, 2026 at 6:00 AM CDT

Rutgers could turn again to AJ Surace after his four-interception game against Boston College, but USC also has an injury to account for.

Rutgers' quarterback decision

Rutgers' ability to protect the ball is central to USC's 21.5-point spread at SPF. Annenberg Media, USC's student-led news outlet, reports that AJ Surace could make a second straight start with Dylan Lonergan's availability unclear. Surace threw for 230 yards and three touchdowns against Boston College, but also threw four interceptions. Repeat those mistakes and Rutgers risks giving USC extra chances to build a covering margin.

Lonergan left the UMass opener with an undisclosed injury. His possible return doesn't establish a case for Rutgers +21.5: his status remains unresolved, and Surace's touchdown production came with costly turnovers.

Winner and betting recommendation

Annenberg Media reports that USC enters 3-0 and averaging 43.3 points, while Rutgers is 0-2. USC is the likely winner, but its offense will be without wide receiver Trent Mosley. Coach Lincoln Riley confirmed Mosley won't play after a knee injury that's expected to sideline him for multiple games.

SPF's -2100 USC moneyline requires a win probability above 95.5% to break even. These results alone don't justify that threshold or establish an edge on either side of the spread. The recommendation is Pass.

The total is 58.5, with over -105 and under -115. Mosley's absence matters to USC's scoring outlook, but Rutgers' unsettled quarterback situation leaves both its production and turnover risk difficult to project. There's no supported total wager.

Pick USC Trojans
Confidence medium
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
Previous Matchups