LSU
Tigers
Spread
-3
NCAAF Predictions
LSU Tigers vs Ole Miss Rebels Predictions
Saturday, September 19, 2026 at 7:30pm EST at Vaught-Hemingway Stadium, Oxford, MS
@
Ole Miss
Rebels
Spread
+3
50%
50%
Spread
LSU Tigers -3
Ole Miss Rebels +3
Moneyline
LSU Tigers -155
Ole Miss Rebels +130
Total
Over 58.5 (-108)
Under 58.5 (-112)
Who wins this game?
Professional Picks
4 available
Professional Picks On This Game
Tom Strickland
Total pick
Frank Obst
Spread pick
Elijah Murtah
Spread pick
Bryan Pratt
Total pick
LSU vs. Ole Miss Prediction: Leavitt Questionable With Tigers Favored by 3
Analysis updated September 18, 2026 at 6:47 AM CDT
Sam Leavitt’s availability is unresolved, leaving a key question for anyone considering LSU at -3 or -148.
Leavitt’s status weighs on LSU’s price
LSU is a 3-point road favorite at Ole Miss, but quarterback Sam Leavitt is questionable, according to LSU coverage site And The Valley Shook. His status leaves a central part of the Tigers’ offense uncertain before a game they must win by at least four points to cover.
The same report lists receiver Phillip Wright III and running back Raycine Guillory Jr. as out. On defense, linebacker TJ Dottery is questionable and defensive back Jaiden Braker is out. Those designations establish availability concerns, but don’t show how much production LSU would lose.
SPF odds and betting decision
SPF lists LSU at -148 on the moneyline and Ole Miss at +124, with the Rebels getting 3 points. The total is 58.5, priced at -110 on either side.
Pass. LSU’s price identifies it as the market favorite, but the available evidence doesn’t support an independent winner prediction or a bet on either team. The injury report alone also doesn’t establish an edge on the total.
Confidence
low
Betting lean
Pass