NCAAF Predictions

Florida State Seminoles vs Alabama Crimson Tide Predictions

Saturday, September 19, 2026 at 3:30pm EST at Bryant-Denny Stadium, Tuscaloosa, AL

Florida State

Seminoles

Spread +19.5
@
Alabama

Crimson Tide

Spread -19.5
50% 50%
Spread Florida State Seminoles +19.5 Alabama Crimson Tide -19.5
Moneyline Florida State Seminoles +800 Alabama Crimson Tide -1350
Total Over 49.5 (-112) Under 49.5 (-108)

Who wins this game?

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Professional Picks On This Game

6 available
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Alabama vs. Florida State: Russell’s Turnovers Matter at -19.5

Analysis updated September 18, 2026 at 5:55 AM CDT

Alabama is the likely winner, but its quarterback’s mistakes at Kentucky give bettors a specific concern about backing a three-score victory.

Can Alabama protect its possessions?

Alabama won 45-17 at Kentucky despite three first-half turnovers by starting quarterback Keelon Russell, according to CBS Sports. Those lost possessions are a concern at SPF’s Alabama -19.5: another win could still leave the Crimson Tide short of covering.

CBS Sports reports that Florida State visits Bryant-Denny Stadium on September 19 at 3:30 p.m. ET after a bye following a 27-24 loss to SMU. The break gave the Seminoles extra preparation time, but that alone doesn’t establish a case for taking +19.5.

Betting verdict

Alabama’s convincing result at Kentucky and home field make it the pick to win. SPF lists the Crimson Tide at -1350 and Florida State at +800, however, and one recent result doesn’t justify paying that moneyline price or projecting a 20-point margin.

SPF’s total is 48.5, with over -112 and under -108. Without a fuller picture of either team’s scoring and defensive performance, there’s no supported total lean. Pass on all listed markets.

Pick Alabama Crimson Tide
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
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