Louisville Cardinals vs NC State Wolfpack Predictions, Odds & Picks

Louisville's big plays come with a coverage risk

Louisville is the more likely winner, but the Cardinals' weaknesses make their -3 spread difficult to back. Card Chronicle, a Louisville sports publication, reports that the Cardinals have scored seven touchdowns of at least 50 yards, the most in FBS, and committed only one turnover through four games. Those numbers support Louisville's -166 moneyline price because the Cardinals can create points quickly without wasting possessions.

The same publication reports that Louisville has allowed four passes of at least 60 yards, the most in the country, and ranks fourth nationally in penalty yardage. One long completion or costly penalty could decide whether the Cardinals cover a field-goal spread on the road.

NC State has a way to challenge the favorite

NC State running back Duke Scott is averaging 6.0 yards per carry and 86 rushing yards per game. He had 25 carries for 148 yards and two touchdowns in his previous game. A productive rushing attack would help the Wolfpack avoid relying only on the deep passes that have hurt Louisville.

Louisville's offensive line was reported healthy, and edge defenders had five sacks through four games. However, the latest report said Louisville had not released its depth chart, and the available information doesn't confirm the starters or provide injury listings. With that uncertainty, neither Louisville -3 nor NC State +3 is a sound wager. The total of 57.5 also lacks enough supporting evidence, so the betting lean is Pass.

Pick Louisville Cardinals

Confidence low

Betting lean Pass

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Louisville Cardinals vs NC State Wolfpack Predictions

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Louisville vs. NC State Prediction: Cardinals More Likely to Win, but Pass at -3

Louisville's big plays come with a coverage risk

NC State has a way to challenge the favorite