SE Louisiana Lions vs Northwestern State Demons Predictions
Saturday, September 26, 2026 at 7:00pm EST
Demons
0-4Professional Picks On This Game
SE Louisiana vs. Northwestern State Prediction: Pass on the 37.5-Point Spread
Analysis updated September 26, 2026 at 8:50 AM CDT
Kyle Lowe has thrown nine touchdown passes for the Lions, while the Demons gained 389 yards and scored 20 points at Weber State last week.
Lowe gives SE Louisiana the edge
SE Louisiana enters Saturday's game at Turpin Stadium with a 2-2 record, while Northwestern State is 0-4. Lions quarterback Kyle Lowe has thrown at least two touchdown passes in every game, totaling nine touchdowns with three interceptions and a 61.8% completion rate. That production makes SE Louisiana the likely winner.
Northwestern State can challenge a large spread
Northwestern State lost 49-20 at Weber State last week, but the Demons gained 389 yards. Zach Wilcke threw three touchdown passes in his first start, four receivers finished with at least 50 yards, and eight players caught a pass. That passing production matters with Northwestern State getting 37.5 points.
The Demons have forced at least two turnovers in each of their past two games and turned three of those four takeaways into touchdowns. Those short-field scoring chances could help Northwestern State stay within the spread even if SE Louisiana wins.
Betting outlook
The SPF spread requires SE Louisiana to win by 38 points. Northwestern State's recent passing and takeaway production makes that margin too difficult to support, so the side is a pass.
No moneyline price is available. The total is 60.5, with both sides priced at -111, but one recent Northwestern State performance isn't enough to project the combined score. Pass on the total.