Oklahoma State
Cowboys
2-1
Spread
+1.5
NCAAF Predictions
Oklahoma State Cowboys vs West Virginia Mountaineers Predictions
Saturday, September 26, 2026 at 7:00pm EST at Milan Puskar Stadium, Morgantown, WV
@
West Virginia
Mountaineers
3-0
Spread
-1.5
50%
50%
Spread
Oklahoma State Cowboys +1.5
West Virginia Mountaineers -1.5
Moneyline
Oklahoma State Cowboys +105
West Virginia Mountaineers -125
Total
Over 61.5 (-105)
Under 61.5 (-115)
Who wins this game?
Professional Picks
2 available
Professional Picks On This Game
Wes Salvato
Total pick
Abe Howland
Total pick
Oklahoma State vs. West Virginia Prediction: Cowboys’ Passing Game Points to a Pass
Analysis updated September 26, 2026 at 2:09 AM CDT
West Virginia is favored at home, but Drew Mestemaker gives Oklahoma State a clear way to challenge the Mountaineers through the air.
Mestemaker tests West Virginia’s pass defense
WV MetroNews reports that Oklahoma State averages 306.3 passing yards per game, tied for first in the Big 12. Quarterback Drew Mestemaker has completed 46 of 65 passes for 641 yards, seven touchdowns and two interceptions over his past two games. That production matters against a West Virginia defense that allowed 367 passing yards across its previous two contests.
Mestemaker’s best recent performance came against Murray State on September 19, when he completed 20 of 22 passes for 324 yards and five touchdowns in a 59-0 win. West Virginia presents a different test, but the Cowboys have shown they can create points through the air. Calm wind in the National Weather Service forecast for Saturday night should not hinder that approach.
West Virginia can win without offering betting value
West Virginia enters 3-0 and has home-field advantage at Milan Puskar Stadium, while Oklahoma State is 2-1. SportsPicksForum makes the Mountaineers a 1.5-point favorite and -125 on the moneyline, with Oklahoma State at +105 and the total at 61.5.
The Mountaineers are the slight pick to win, but the available evidence does not justify laying -125 or 1.5 points. There is no confirmed injury report, starting-lineup information or broader statistical comparison, and the listed 50-50 betting split is only a default figure. Those gaps don’t create value on Oklahoma State; they make the proper betting decision a pass.
Pick
West Virginia Mountaineers
Confidence
low
Betting lean
Pass