South Carolina
Gamecocks
Spread
+12.5
NCAAF Predictions
South Carolina Gamecocks vs Alabama Crimson Tide Predictions
Saturday, September 26, 2026 at 7:00pm EST at Bryant-Denny Stadium, Tuscaloosa, AL
@
Alabama
Crimson Tide
Spread
-12.5
50%
50%
Spread
South Carolina Gamecocks +12.5
Alabama Crimson Tide -12.5
Moneyline
South Carolina Gamecocks +390
Alabama Crimson Tide -520
Total
Over 54.5 (-108)
Under 54.5 (-112)
Who wins this game?
Professional Picks
2 available
Professional Picks On This Game
Lane Gibson
Spread pick
Brooke Smolka
Spread pick
South Carolina vs. Alabama Prediction: Back the Tide to Win, but Pass at -485
Analysis updated September 25, 2026 at 8:25 AM CDT
Alabama is the likely winner at home, but neither its -485 moneyline nor the 12.5-point spread offers a supportable wager with key matchup details unavailable.
Alabama’s record supports the favorite, not the price
Alabama Athletics reports that the Crimson Tide enter Saturday’s home game against South Carolina unbeaten through three games. Alabama also beat Florida State 50-36 in Tuscaloosa in its previous game, making the Tide the more supportable pick to win.
SportsPicksForum prices Alabama at -485 on the moneyline and -12.5 against the spread, with South Carolina at +370 and +12.5. The favorite’s moneyline requires too large an investment when no South Carolina form, injury, starter or matchup statistics are available.
Florida State’s 36 points against Alabama do not predict South Carolina’s output, but that result offers no clear reason to lay 12.5 points. Without evidence that Alabama can create a two-touchdown margin in this matchup, the betting lean is Pass.
Pick
Alabama Crimson Tide
Confidence
low
Betting lean
Pass