Southern Miss
Golden Eagles
Spread
+17.5
NCAAF Predictions
Southern Miss Golden Eagles vs Tulane Green Wave Predictions
Saturday, September 26, 2026 at 7:00pm EST at Yulman Stadium, New Orleans, LA
@
Tulane
Green Wave
Spread
-17.5
50%
50%
Spread
Southern Miss Golden Eagles +17.5
Tulane Green Wave -17.5
Moneyline
Southern Miss Golden Eagles +700
Tulane Green Wave -1100
Total
Over 52.5 (-108)
Under 52.5 (-112)
Who wins this game?
Professional Picks
1 available
Professional Picks On This Game
Lane Gibson
Total pick
Southern Miss vs. Tulane Prediction: Pass on the Heavy Favorite
Analysis updated September 25, 2026 at 8:29 AM CDT
Southern Miss quarterback Ethan Hampton is out, strengthening Tulane's case as the likely winner. The available evidence doesn't support laying 18.5 points or risking -1050 on the moneyline.
Hampton's absence favors Tulane
Covers, a sports betting news and data publication, lists Southern Miss quarterback Ethan Hampton out with a hand injury and wide receiver G. Page out with an elbow injury. Those absences weaken the case for a Golden Eagles upset and support Tulane as the likely winner.
Tulane also has backfield and receiving questions. Running back Jamauri McClure is out with a foot injury, while receiver Zycarl Lewis Jr. is questionable because of a leg injury. Lewis' unresolved status adds risk to any Tulane bet.
The prices demand more evidence
SPF lists Tulane as an 18.5-point favorite with a -1050 moneyline. Southern Miss is +675, and the total is 52.5. Hampton's absence matters, but no confirmed replacement, recent results or season statistics are available to show that Tulane can cover such a large spread.
The injury report also doesn't establish an edge on the total. With limited performance data and uncertainty around Tulane's available receivers, neither over 52.5 nor under 52.5 is supportable. Tulane is the likely winner, but the wager is a pass.
Pick
Tulane Green Wave
Confidence
low
Betting lean
Pass