NCAAF Predictions

West Florida Argonauts vs Southeast Missouri State Redhawks Predictions

Saturday, September 26, 2026 at 7:00pm EST at Houck Field, Cape Girardeau, MO

West Florida

Argonauts

Spread +6
@
Southeast Missouri State

Redhawks

Spread -6
50% 50%
Spread West Florida Argonauts +6 Southeast Missouri State Redhawks -6
Moneyline West Florida Argonauts +155 Southeast Missouri State Redhawks -195
Total Over 52.5 (-111) Under 52.5 (-111)

Who wins this game?

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West Florida vs. Southeast Missouri State Prediction: Redhawks Favored by 6

Analysis updated September 26, 2026 at 2:29 AM CDT

Southeast Missouri State is the likelier winner at home, but the available evidence does not support a wager on the spread or total.

Matchup outlook

Southeast Missouri State is a 6-point home favorite after beating Central Arkansas 27-9. West Florida enters the Sept. 26 game at 2-1 after a 38-16 loss to No. 11 Austin Peay. University of West Florida Athletics notes that this will be the programs’ first meeting.

West Florida quarterback Ty'ray Davis is expected to be at full speed after he was injured against Austin Peay. Davis has passed for 454 yards and six touchdowns in three starts, and he leads the Argonauts with 182 rushing yards and three scores. His ability to run gives West Florida a chance to challenge the favorite.

Injuries and matchup questions

West Florida running back TJ Lane’s status remains uncertain. Markel Townsend would become the featured back if Lane cannot play, leaving an important part of the Argonauts’ offense unsettled before kickoff.

Southeast Missouri State quarterback Braylen Ragland ranks second in the Ohio Valley Conference with 225.5 passing yards per game. The Redhawks also have home field against a West Florida team that traveled 593 miles by bus to Cape Girardeau. Those factors favor Southeast Missouri State, but they do not establish that the Redhawks should cover 6 points.

Prediction and betting lean

Southeast Missouri State is the more likely winner and is priced accordingly at -195. However, there is no confirmed lineup for West Florida’s backfield, no sourced line movement and no reliable public-betting split. The total of 52.5 also lacks enough supporting evidence. Pass on the spread, moneyline and total.

Pick Southeast Missouri State Redhawks
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.