Toronto
Blue Jays
77-80
Moneyline
+102
MLB Predictions
Toronto Blue Jays vs Baltimore Orioles Predictions
Tuesday, September 22, 2026 at 6:35pm EST at Oriole Park at Camden Yards, Baltimore, Maryland
@
Baltimore
Orioles
76-81
Moneyline
-123
25%
75%
Spread
Toronto Blue Jays +1.5
Baltimore Orioles -1.5
Moneyline
Toronto Blue Jays +102
Baltimore Orioles -123
Total
Over 7 (-122)
Under 7 (+101)
Professional Picks
1 listed
Professional Picks On This Game
Stevie March
Total pick
Orioles vs. Blue Jays Prediction: Bassitt’s ERA Edge Favors Baltimore
Analysis updated September 22, 2026 at 5:04 AM CDT
Baltimore gets the tentative winner pick on the probable pitching matchup. That alone doesn’t justify a wager at -122.
Probable starters favor Baltimore
Chris Bassitt’s 4.64 ERA is the clearest reason to favor Baltimore against Toronto on Tuesday at Camden Yards. FanDuel Research / Data Skrive, a sports betting research publisher, lists Bassitt and Toronto’s Max Scherzer, who has a 6.07 ERA, as the probable starters. SPF prices the Orioles at -122 and the Blue Jays at +101.
The same report lists Pete Alonso with a .359 on-base percentage and .510 slugging percentage, giving Baltimore a productive bat behind Bassitt. But without confirmed lineups or bullpen availability, those numbers don’t establish that Baltimore’s win probability clears the roughly 55% needed to justify -122. Baltimore is the tentative winner pick; the wager is a pass.
No bet on the total
SPF’s total is 7.5, with over -114 and under -106. FanDuel Research / Data Skrive reports that Baltimore went over in 79 of 155 games and Toronto in 80 of 152. Those results came against varying totals and don’t establish an edge at 7.5. With the starters still probable and no confirmed weather or bullpen context, pass on the total.
Pick
Baltimore Orioles
Confidence
low
Betting lean
Pass