Houston
Astros
Moneyline
+123
MLB Predictions
Houston Astros vs Seattle Mariners Predictions
Tuesday, September 22, 2026 at 9:40pm EST at T-Mobile Park, Seattle, Washington
@
Seattle
Mariners
Moneyline
-149
50%
50%
Spread
Houston Astros +1.5
Seattle Mariners -1.5
Moneyline
Houston Astros +123
Seattle Mariners -149
Total
Over 7.5 (-112)
Under 7.5 (-108)
Who wins this game?
Professional Picks
4 available
Professional Picks On This Game
Tom Strickland
Spread pick
Matt O'Brien
Spread pick
Wes Salvato
Spread pick
Abe Howland
Total pick