Tampa Bay
Rays
Moneyline
+113
MLB Predictions
Tampa Bay Rays vs New York Yankees Predictions
Tuesday, September 22, 2026 at 7:05pm EST at Yankee Stadium, Bronx, New York
@
New York
Yankees
Moneyline
-137
50%
50%
Spread
Tampa Bay Rays +1.5
New York Yankees -1.5
Moneyline
Tampa Bay Rays +113
New York Yankees -137
Total
Over 6.5 (-120)
Under 6.5 (+100)
Who wins this game?
Professional Picks
3 available
Professional Picks On This Game
Rays vs. Yankees Prediction: Rasmussen Makes Tampa Bay Worth a Look at +113
Analysis updated September 21, 2026 at 11:11 PM CDT
The probable starters have similar ERAs, and New York will play without Aaron Judge. That makes the Rays an appealing underdog, though Max Fried keeps confidence low.
A close pitching matchup
Drew Rasmussen's 2.72 ERA gives Tampa Bay a strong starter to oppose Max Fried and the Yankees at SPF's -137. Sports news outlet Heavy lists Rasmussen and Fried as the probable pitchers for Tuesday's 7:05 p.m. EDT nightcap, with Fried carrying a 2.63 ERA and 0.98 WHIP through 106 innings. Neither assignment is confirmed.
New York will also be without Aaron Judge. Pinstripe Alley / SB Nation via Yahoo Sports, a Yankees-focused publication, reports that Judge returned to the injured list and will miss the series. His absence tips my winner pick toward Tampa Bay, with a low-confidence moneyline lean at SPF's +113.
Pass on the total
The same series preview reports that Tampa Bay averaged 5.7 runs over its previous 10 games and New York averaged 5.4. Those short stretches don't establish what either lineup will do against these starters, but they caution against taking the under solely because of the pitchers' ERAs.
SPF lists the total at 6.5, with over -120 and under +100. This is the second game of a split doubleheader, so the afternoon game's bullpen use could affect the nightcap. Without that information or confirmed lineups, the total is a pass.
Pick
Tampa Bay Rays
Confidence
low
Betting lean
Tampa Bay Rays moneyline +113