Philadelphia Eagles vs Jacksonville Jaguars Predictions

Philadelphia must rebuild its offense in London

NFL.com reports that Philadelphia ruled out running back Saquon Barkley and receivers Marquise Brown and DeVonta Smith. The Eagles also expect Will Shipley to handle the heavier running-back workload with Barkley and Tank Bigsby unavailable. Those absences help explain why Jacksonville is favored by 7.5 points at Tottenham Hotspur Stadium.

The Philadelphia Eagles project an offensive line of Jordan Mailata, Willie Lampkin, Jake Majors, Tyler Steen and Markel Bell, a group the team describes as raw and inexperienced. Drew Kendall is out, while Lane Johnson retired and Cam Jurgens was traded during the week. That much change up front strengthens Jacksonville’s case to win, although Fred Johnson’s return gives Philadelphia another available tackle.

Dallas Goedert returns after missing two games with a knee injury, and Jacksonville will be without cornerback Jaylon Jones while safety Eric Murray is doubtful. Those developments give Philadelphia some hope in the passing game, but they do not offset all of its confirmed absences.

Jacksonville is the pick, but Pass is the bet

Jacksonville enters at 3-1, while Philadelphia is coming off a 24-20 loss to the Los Angeles Rams, according to the Philadelphia Eagles’ official preview. Combined with the Eagles’ lineup losses, that makes Jacksonville the more likely winner.

The Jaguars cost -380 on the SPF moneyline, and backing them at -7.5 requires a win by more than a touchdown. The available evidence supports Jacksonville straight up but does not establish enough of an edge at either price. The 41.5 total also lacks sufficient matchup data, so the betting lean is Pass.