NFL Predictions

New England Patriots vs Jacksonville Jaguars Predictions

Sunday, September 27, 2026 at 1:00pm EST at EverBank Stadium, Jacksonville, FL

New England

Patriots

Spread +3
@
Jacksonville

Jaguars

Spread -3
50% 50%
Spread New England Patriots +3 Jacksonville Jaguars -3
Moneyline New England Patriots +130 Jacksonville Jaguars -155
Total Over 45.5 (-115) Under 45.5 (-105)

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Patriots vs. Jaguars Prediction: Pick Jacksonville, Pass at -3

Analysis updated September 27, 2026 at 1:16 AM CDT

The Jaguars enter Week 3 at 1-1 after struggling to protect Trevor Lawrence in Denver. That concern makes Jacksonville easier to pick outright than to back at the SPF price.

Matchup outlook

Jacksonville has won 10 of its past 11 regular-season games, according to the Jacksonville Jaguars, and hosts New England at EverBank Stadium. That recent record makes the Jaguars the likelier winner, but SPF's -155 moneyline and -3 spread leave little room for another uneven performance.

Jacksonville's pass protection struggled during its Week 2 loss at Denver, where the Jaguars led for much of the game before losing by seven. Protection problems around Trevor Lawrence could help Drake Maye and New England stay within a field goal.

Betting view

New England linebacker Dre'Mont Jones is out with a shoulder injury, the New England Patriots reported. Tight end Eli Raridon and safety Craig Woodson are questionable after traveling with the team, and Raridon missed practice Thursday and Friday. Those absences don't provide a clear reason to back either side of the spread.

The total is 45.5, with the over priced at -115 and the under at -105. There isn't enough scoring, defensive or weather information to support a total bet. The listed 50-50 moneyline percentages are defaults rather than reported betting activity, so they carry no weight in the pick.

Pick Jacksonville Jaguars
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
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