NFL Predictions

New York Jets vs Detroit Lions Predictions

Sunday, September 27, 2026 at 1:00pm EST

New York

Jets

Spread +7
@
Detroit

Lions

Spread -7
50% 50%
Spread New York Jets +7 Detroit Lions -7
Moneyline New York Jets +260 Detroit Lions -325
Total Over 49.5 (-115) Under 49.5 (-105)
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Jets vs. Lions Prediction: Detroit’s Passing Game Points to a Win, Not a Bet

Analysis updated September 27, 2026 at 7:09 AM CDT

Detroit’s productive passing game makes the Lions the likelier winner. The -305 moneyline and 6.5-point spread demand more certainty than the available matchup data provides.

Detroit’s passing game drives the prediction

The Detroit Lions’ official website reports that Jared Goff completed 26 of 38 passes for 327 yards and four touchdowns in last week’s 41-31 loss at Buffalo. Amon-Ra St. Brown added 142 receiving yards and two touchdowns, while Jahmyr Gibbs and Sam LaPorta each caught a touchdown. That production makes Detroit the likely winner at Ford Field, but the SPF price requires bettors to lay -305 on the moneyline or 6.5 points on the spread.

Both teams enter Week 3 at 1-1. New York lost 20-17 to Green Bay last week, but the available evidence includes no season statistics or confirmed starters that would support a reliable estimate of the margin. Detroit may win without covering, so neither Lions price offers enough value to wager.

Injuries and the total

Jets X-Factor, an independent publication covering the Jets, reports that New York safety Minkah Fitzpatrick, linebacker Kiko Mauigoa, tight end Mason Taylor, and running back and returner Kene Nwangwu are out. Wide receiver Adonai Mitchell and edge rusher Joseph Ossai are questionable. Those absences favor Detroit, but their effect on the point spread can’t be measured from the available information.

Detroit guard Ben Bartch and safety Thomas Harper are out, according to Jets X-Factor. Tackle Blake Miller and guards Christian Mahogany and Tate Ratledge practiced fully Friday and no longer had injury designations, reducing the Lions’ reported concerns along the offensive line.

The total is 48.5, with the over at -108 and the under at -112. Detroit scored 31 points at Buffalo, but there isn’t enough evidence about either defense or the Jets’ scoring ability to support either side. Pass on the total and the game lines.

Pick Detroit Lions
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
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