Philadelphia
76ers
3-1
Spread
-4.5
NBA Predictions
Philadelphia 76ers vs Indiana Pacers Predictions
Wednesday, October 28, 2026 at 7:00pm EST at Gainbridge Fieldhouse, Indianapolis, IN
@
Indiana
Pacers
2-2
Spread
+4.5
50%
50%
Spread
Philadelphia 76ers -4.5
Indiana Pacers +4.5
Moneyline
Philadelphia 76ers -170
Indiana Pacers +142
Total
Over 237.5 (-110)
Under 237.5 (-110)
Who wins this game?
Professional Picks
3 available
Professional Picks On This Game
76ers vs. Pacers Prediction: Indiana Injuries Make -166 Hard to Back
Analysis updated October 28, 2026 at 1:01 AM CDT
The 76ers entered 3-1, but uncertainty surrounding Indiana's rotation makes Philadelphia's moneyline difficult to price. The pick is Philadelphia to win, with no wager.
Indiana's availability is the key betting question
The Indiana Pacers' official NBA.com preview reported that only 10 players were active for Monday's 110-102 loss at Milwaukee. Ivica Zubac missed that game after spraining an ankle Sunday, Andrew Nembhard sat with a sore neck, and T.J. McConnell, Ben Sheppard and Johnny Furphy were unavailable. Aaron Nesmith played under a minutes restriction while returning from a hamstring strain. Their status for Wednesday isn't confirmed, so Indiana's rotation can't be assessed with confidence.
Indiana still has a clear threat in Tyrese Haliburton, who averaged 21.8 points and 9.5 assists while shooting 51.6% through four games. That production matters against a 4.5-point spread, but it doesn't establish value on the Pacers without knowing who will join him.
Philadelphia should win, but the price is too high
Philadelphia entered the matchup 3-1, compared with Indiana's 2-2 record. The Pacers' preview also noted that Tyrese Maxey scored 32 points and Paul George added 21 in the 76ers' most recent game, supporting Philadelphia as the likely winner.
SPF lists Philadelphia at -166 on the moneyline and -4.5 on the spread. The 76ers have the stronger early record, but neither price is worth taking before Indiana's available lineup is known. Pass on both markets.
Pick
Philadelphia 76ers
Confidence
low
Betting lean
Pass