NFL Predictions

Dallas Cowboys vs Philadelphia Eagles Predictions

Monday, October 26, 2026 at 8:15pm EST at Lincoln Financial Field, Philadelphia, PA

Dallas

Cowboys

Spread -4.5
@
Philadelphia

Eagles

Spread +4.5
50% 50%
Spread Dallas Cowboys -4.5 Philadelphia Eagles +4.5
Moneyline Dallas Cowboys -218 Philadelphia Eagles +180
Total Over 43.5 (-115) Under 43.5 (-105)

Who wins this game?

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Cowboys vs. Eagles Prediction: Injuries Favor Dallas, but the Price Is Steep

Analysis updated October 25, 2026 at 7:42 AM CDT

Tanner McKee will start for Philadelphia with two wide receivers out, making Dallas the likelier winner. The Cowboys are not an appealing bet at -218 or -4.5.

Cowboys vs. Eagles odds

Dallas is a -218 moneyline favorite and lays 4.5 points Monday night in Philadelphia. The Eagles are +180 and +4.5, while the total is 43.5 with the over at -118 and the under at -102.

Philadelphia's absences favor Dallas

The Philadelphia Inquirer reports that Tanner McKee will start while Jalen Hurts receives treatment for blood clots. Philadelphia has lost four straight and will be without wide receivers DeVonta Smith and Dontayvion Wicks, leaving McKee with fewer proven targets.

Saquon Barkley is questionable with a hamstring injury after missing the previous two games and most of the game before them. He practiced fully Saturday, but uncertainty about his workload makes Philadelphia difficult to back.

Prediction and betting outlook

Dallas also enters on a losing streak, and both offenses have struggled recently. Those concerns make the Cowboys' -218 moneyline too costly and leave too little evidence to trust them at -4.5.

Dallas is the likelier winner because Philadelphia is starting McKee without Smith or Wicks, but the available information doesn't support a wager. Pass.

Pick Dallas Cowboys
Confidence low
Betting lean Pass
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