Indianapolis
Colts
Spread
+6.5
NFL Predictions
Indianapolis Colts vs Minnesota Vikings Predictions
Sunday, October 25, 2026 at 1:00pm EST at U.S. Bank Stadium, Minneapolis, MN
@
Minnesota
Vikings
Spread
-6.5
50%
50%
Spread
Indianapolis Colts +6.5
Minnesota Vikings -6.5
Moneyline
Indianapolis Colts +260
Minnesota Vikings -325
Total
Over 41.5 (-110)
Under 41.5 (-110)
Who wins this game?
Professional Picks
7 available
Professional Picks On This Game
Tom Strickland
Total pick
Eli Rothstein
Total pick
Brooke Smolka
Total pick
King Jon Sanderson
Spread pick
Scott Steele
Spread pick
Bryan Pratt
Spread pick
Robert Downes
Total pick
Colts vs. Vikings Prediction: Pass on Minnesota at -6.5
Analysis updated October 25, 2026 at 1:07 AM CDT
The Vikings are the likely winner, but their -325 moneyline and 6.5-point spread require more support than the available matchup information provides.
Colts vs. Vikings prediction
Minnesota is favored by 6.5 points at home, with a -325 moneyline compared with Indianapolis at +260. Those prices make the Vikings the likely winner, but neither offers clear betting value without reliable information on the starting lineups, recent form or team performance.
The 41.5-point total is also a pass. There isn't enough evidence to judge how either offense matches up with the opposing defense, so projecting the game's scoring would require unsupported assumptions.
CJ Allen ruled out
CBS Sports / RotoWire reported that Colts linebacker CJ Allen will miss Sunday's game with an ankle injury after Indianapolis downgraded him from questionable to out Saturday. His absence hurts the Colts' defensive depth, but one confirmed injury isn't enough to justify laying 6.5 points with Minnesota.
Pick
Minnesota Vikings
Confidence
low
Betting lean
Pass