MLB Predictions

Cincinnati Reds vs Toronto Blue Jays Predictions

Friday, September 25, 2026 at 7:07pm EST at Rogers Centre, Toronto, Ontario

Cincinnati

Reds

74-85
Moneyline +133
@
Toronto

Blue Jays

77-82
Moneyline -161
50% 50%
Spread Cincinnati Reds +1.5 Toronto Blue Jays -1.5
Moneyline Cincinnati Reds +133 Toronto Blue Jays -161
Total Over 7.5 (-114) Under 7.5 (-105)
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Reds vs. Blue Jays Prediction: Soriano Favors Toronto, but Pass at -136

Analysis updated September 25, 2026 at 7:17 AM CDT

Toronto has the stronger listed probable starter, but its low-scoring offense and three-game losing streak make the -136 moneyline difficult to back.

Soriano gives Toronto the pitching edge

Fox Sports 980 WONE / iHeartMedia lists José Soriano as Toronto’s probable starter and Nick Lodolo for Cincinnati. Soriano has a 3.77 ERA, 1.262 WHIP and 8.6 strikeouts per nine innings in 31 starts. Lodolo has a 5.04 ERA, 1.466 WHIP and 6.9 strikeouts per nine in 20 starts. That difference makes Toronto the more likely winner, though neither starter has been confirmed.

Why the price is too high

Toronto has averaged 4.0 runs per game and hit 150 home runs, both reported as the lowest marks in MLB. Cincinnati has averaged 4.1 runs and hit 211 homers. The Blue Jays’ .248 batting average is better than the Reds’ .228 mark, but Toronto’s limited power makes both the -136 moneyline and -1.5 run line hard to justify.

The Blue Jays enter on a three-game losing streak and hold a 77-82 record, while Cincinnati is 74-85. Soriano’s advantage points to Toronto, but the available evidence doesn’t establish enough separation to recommend paying the favorite’s price. Pass.

Pick Toronto Blue Jays
Confidence low
Betting lean Pass
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