Pittsburgh
Pirates
81-78
Moneyline
-101
MLB Predictions
Pittsburgh Pirates vs Detroit Tigers Predictions
Friday, September 25, 2026 at 6:40pm EST at Comerica Park, Detroit, Michigan
@
Detroit
Tigers
74-85
Moneyline
-119
50%
50%
Spread
Pittsburgh Pirates -1.5
Detroit Tigers +1.5
Moneyline
Pittsburgh Pirates -101
Detroit Tigers -119
Total
Over 8 (-104)
Under 8 (-115)
Professional Picks
8 listed
Professional Picks On This Game
Tom Strickland
Money pick
Wes Salvato
Money pick
Jeff Ross
Money pick
Jonah Black
Money pick
Jonah Black
Total pick
Dave Vernin
Total pick
Abe Howland
Money pick
Garrett Perry
Total pick
Pirates vs. Tigers Prediction: Pass on Near Pick’em Price
Analysis updated September 25, 2026 at 7:08 AM CDT
The Pirates are the narrow pick to win at Detroit, but Pittsburgh at -109 offers no clear betting edge over the Tigers at -110.
Detroit’s pitching matchup narrows the gap
The Associated Press lists Pittsburgh right-hander Bubba Chandler and Detroit right-hander Jackson Jobe as the probable starters for the Sept. 25 series opener at Comerica Park. Chandler is 8-9 with a 4.34 ERA and 1.37 WHIP, while Jobe is 2-3 with a 3.98 ERA and 1.21 WHIP. Jobe’s lower ERA and WHIP help explain why Detroit is a slight -110 favorite despite its worse overall record.
Pittsburgh enters at 81-78, compared with Detroit at 74-85, but the teams’ location splits point in different directions. The Pirates are 37-41 on the road, and the Tigers are 40-38 at home. Pittsburgh’s better season record makes it the narrow choice to win, though not a strong enough one to justify laying -109.
Why the best wager is a pass
Detroit is 4-6 over its past 10 games, with a .267 batting average and 3.56 ERA during that stretch. Those results don’t provide a clear reason to back the Tigers at -110, while the probable pitching comparison makes Pittsburgh difficult to price as the better bet.
The total is 8, with the under at -118 and the over at -102. No confirmed lineup, bullpen availability, injury or weather information is available to support either side of that market. The same limitation applies to Pittsburgh -1.5 and Detroit +1.5 on the run line, so the wager is Pass.
Pick
Pittsburgh Pirates
Confidence
low
Betting lean
Pass