Chicago Cubs vs Cincinnati Reds Predictions
Sunday, September 20, 2026 at 1:40pm EST
Reds
72-83Professional Picks On This Game
No professional picks are available for this matchup.
Cubs vs. Reds Prediction: Pitching Risk Limits Chicago's Betting Appeal
Analysis updated September 20, 2026 at 5:36 AM CDT
Chicago gets the winner pick against a struggling Cincinnati staff. Paying -155 is a separate decision.
Reds' pitching slump favors the Cubs
Cincinnati has a 7.86 ERA over its last 10 games and has been outscored by 46 runs, according to FOX Sports / Associated Press. Chicago has a 3.78 ERA over that stretch. The pitching gap helps explain why SPF lists the Cubs at -155, a price that requires winning about 60.8% of the time to break even.
Chicago also leads the season series 8-4 and enters Sunday at 86-69, compared with Cincinnati's 72-83. Those results make the Cubs the winner pick, but they don't establish that the moneyline offers value.
Probable starters leave little margin at this price
The report lists David Peterson and Rhett Lowder as the probable starters. Peterson carries a 5.11 ERA and 1.55 WHIP for Chicago; Lowder has a 5.79 ERA and 1.52 WHIP for Cincinnati. Peterson's own struggles allowing runs temper Chicago's advantage enough to pass on the -155 moneyline.
SPF's total is 10, with over -104 and under -116. The starters' ERAs point toward scoring, but Cincinnati's .216 batting average over its last 10 games weakens the case for the over. Neither side of the total warrants a bet.