Jacksonville
Jaguars
Spread
+3
NFL Predictions
Jacksonville Jaguars vs Denver Broncos Predictions
Sunday, September 20, 2026 at 4:05pm EST at Empower Field at Mile High, Denver, CO
@
Denver
Broncos
Spread
-3
50%
50%
Spread
Jacksonville Jaguars +3
Denver Broncos -3
Moneyline
Jacksonville Jaguars +130
Denver Broncos -155
Total
Over 45.5 (-108)
Under 45.5 (-112)
Who wins this game?
Professional Picks
6 available
Professional Picks On This Game
Matt O'Brien
Spread pick
Abe Howland
Total pick
Frank Obst
Spread pick
Charles Avery
Spread pick
Charles Avery
Total pick
Benjamin Sturn
Total pick
Jaguars vs. Broncos: Denver's Injuries Give Pause at -3
Analysis updated September 19, 2026 at 11:18 PM CDT
Denver has questions at receiver and running back, but Jacksonville's better availability alone doesn't make the underdog a bet.
Availability matters at this price
Denver is giving Jacksonville 3 points at SportsPicksForum with receiver Marvin Mims Jr. out because of a foot injury. Sports publication Athlon Sports also reports that running back RJ Harvey is questionable with a hamstring injury after limited Friday participation. Mims' absence removes a receiving option, while Harvey's status leaves Denver's backfield availability unsettled.
Jacksonville has no final game-status designations, according to Athlon Sports. That doesn't mean every player is injury-free: running back LeQuint Allen Jr. and receivers Jakobi Meyers and Brian Thomas Jr. were limited with hip, thumb and shoulder injuries, respectively.
Results favor caution, not a firm pick
The Jacksonville Jaguars' official pregame analysis notes that Jacksonville beat Cleveland in Week 1, while Denver lost 31-10 to Kansas City. It also records Jacksonville's 34-20 win at Denver last season. Those results give little reason to favor Denver confidently, but they don't establish how these teams match up now.
SPF lists Denver at -155 and Jacksonville at +130, with a total of 45.5. Pass: the injury report and recent scores don't establish a clear edge against those prices. There's also too little scoring evidence to support a total bet or an exact-score prediction.
Confidence
low
Betting lean
Pass