MLB Predictions

Tampa Bay Rays vs New York Yankees Predictions

Wednesday, September 23, 2026 at 7:05pm EST at Yankee Stadium, Bronx, New York

Tampa Bay

Rays

Moneyline +129
@
New York

Yankees

Moneyline -156
50% 50%
Spread Tampa Bay Rays +1.5 New York Yankees -1.5
Moneyline Tampa Bay Rays +129 New York Yankees -156
Total Over 7 (-105) Under 7 (-114)

Who wins this game?

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Rays vs. Yankees Prediction: Cole's ERA Edge Meets a -155 Price

Analysis updated September 22, 2026 at 11:08 PM CDT

New York gets a slight nod with Cole listed to start, but that doesn't establish value at SPF's price.

Probable pitchers and price

Gerrit Cole's 3.63 ERA against Ian Seymour's 4.38 gives the Yankees the clearest statistical edge for Wednesday's matchup. NYC Sports Wire, a New York sports outlet, lists Cole and Tampa Bay left-hander Seymour as the probable starters. That favors New York, though ERA alone doesn't show whether the Yankees deserve SPF's -155 moneyline, which requires a win rate of about 60.8% to break even.

Tampa Bay brings the stronger record. The official team report from MLB.com / New York Yankees puts the Rays at 96-61 and New York at 90-67 after Tuesday's doubleheader split. The Yankees won the opener 2-0 before Tampa Bay clinched the AL East with a 6-1 victory. Those results don't establish a betting edge for either side.

Betting decision

The Yankees are a low-confidence winner pick based on the probable pitching matchup. Pass on the wager: confirmed lineups and current bullpen availability aren't established, and those details matter after a doubleheader. Tampa Bay's +128 price doesn't become value simply because New York is difficult to back.

SPF lists the total at 7, with over -107 and under -113. The starters' ERAs offer too little to support a totals bet without a clearer view of the hitters and available relievers.

Pick New York Yankees
Confidence low
Betting lean Pass
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