Jacksonville
Jaguars
1-0
Spread
+2.5
NFL Predictions
Jacksonville Jaguars vs Denver Broncos Predictions
Sunday, September 20, 2026 at 4:05pm EST at Empower Field at Mile High, Denver, CO
@
Denver
Broncos
0-1
Spread
-2.5
50%
50%
Spread
Jacksonville Jaguars +2.5
Denver Broncos -2.5
Moneyline
Jacksonville Jaguars +124
Denver Broncos -148
Total
Over 45.5 (-110)
Under 45.5 (-110)
Who wins this game?
Professional Picks
6 available
Professional Picks On This Game
Matt O'Brien
Spread pick
Abe Howland
Total pick
Frank Obst
Spread pick
Charles Avery
Spread pick
Charles Avery
Total pick
Benjamin Sturn
Total pick
Jaguars vs. Broncos: Jacksonville’s Pass Rush Tests Denver at -3
Analysis updated September 20, 2026 at 5:56 AM CDT
Jacksonville’s opening pass-rush performance gives Denver something to address, but one game doesn’t establish a betting edge.
Jacksonville brings pressure
Jacksonville recorded five sacks and allowed just one in its opening win over Cleveland, according to the Jacksonville Jaguars’ official team preview. That makes pass protection a key question for Denver, which SPF lists as a 3-point home favorite. The sack totals are encouraging for Jacksonville, though they don’t establish how either team will handle this matchup.
The same preview reports that Denver allowed Kansas City 5.8 yards per rushing attempt in a 31-10 loss. That gives Jacksonville another potential route to sustaining drives, but without evidence of the Jaguars’ rushing production, it’s too early to assume they can exploit it.
Betting decision
SPF prices Denver at -155 and Jacksonville at +130, with a total of 45.5. Denver is the market favorite; the available performance evidence doesn’t justify an independent winner pick or a wager on either side. Pass on the spread, moneyline and total.
The Jacksonville Jaguars also announced quarterback Nick Mullens’ elevation from the practice squad. That move alone doesn’t identify the starter or establish a quarterback change, so it shouldn’t drive a bet.
Confidence
low
Betting lean
Pass