NBA Predictions

Denver Nuggets vs Oklahoma City Thunder Predictions

Thursday, October 22, 2026 at 9:30pm EST at Paycom Center, Oklahoma City, OK

Denver

Nuggets

Spread +8.5
@
Oklahoma City

Thunder

Spread -8.5
50% 50%
Spread Denver Nuggets +8.5 Oklahoma City Thunder -8.5
Moneyline Denver Nuggets +270 Oklahoma City Thunder -340
Total Over 236.5 (-108) Under 236.5 (-112)

Who wins this game?

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Nuggets vs. Thunder Prediction: Oklahoma City Favored in Denver’s Opener

Analysis updated October 22, 2026 at 7:26 AM CDT

The Thunder have already won once this season and took three of four from Denver last season. Oklahoma City is the likely winner, but its -340 moneyline offers little room for uncertainty.

Thunder have the early edge

The Associated Press reports that Oklahoma City opened its season with a 116-104 road win over San Antonio on October 20. Chet Holmgren contributed 14 points, seven rebounds and four blocks. The Thunder also won three of four meetings with Denver last season, supporting their status as 8.5-point home favorites.

Denver is making its season debut with Nikola Jokic, Jamal Murray and Aaron Gordon back in its starting core. No confirmed starters or injury information is available, so there isn’t enough current evidence to determine whether the Nuggets can stay within 8.5 points.

Betting verdict

Oklahoma City is the likelier winner, but a -340 moneyline requires risking $340 to win $100. That price is too steep without confirmed availability for either team. The 235.5 total also lacks supporting pace or lineup information, leaving no sound case for the over or under. Pass.

Pick Oklahoma City Thunder
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
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