Denver Nuggets vs Oklahoma City Thunder Predictions
Thursday, October 22, 2026 at 9:30pm EST at Paycom Center, Oklahoma City, OK
Thunder
Who wins this game?
Professional Picks On This Game
Nuggets vs. Thunder Prediction: Oklahoma City Favored in Denver’s Opener
Analysis updated October 22, 2026 at 7:26 AM CDT
The Thunder have already won once this season and took three of four from Denver last season. Oklahoma City is the likely winner, but its -340 moneyline offers little room for uncertainty.
Thunder have the early edge
The Associated Press reports that Oklahoma City opened its season with a 116-104 road win over San Antonio on October 20. Chet Holmgren contributed 14 points, seven rebounds and four blocks. The Thunder also won three of four meetings with Denver last season, supporting their status as 8.5-point home favorites.
Denver is making its season debut with Nikola Jokic, Jamal Murray and Aaron Gordon back in its starting core. No confirmed starters or injury information is available, so there isn’t enough current evidence to determine whether the Nuggets can stay within 8.5 points.
Betting verdict
Oklahoma City is the likelier winner, but a -340 moneyline requires risking $340 to win $100. That price is too steep without confirmed availability for either team. The 235.5 total also lacks supporting pace or lineup information, leaving no sound case for the over or under. Pass.