Chicago
White Sox
Moneyline
+134
MLB Predictions
Chicago White Sox vs Cleveland Guardians Predictions
Monday, September 14, 2026 at 6:40pm EST
@
Cleveland
Guardians
Moneyline
-162
14%
86%
Spread
Chicago White Sox +1.5
Cleveland Guardians -1.5
Moneyline
Chicago White Sox +134
Cleveland Guardians -162
Total
Over 7 (-102)
Under 7 (-119)
Professional Picks
5 listed
Professional Picks On This Game
Matt O'Brien
Spread pick
Kit Wilson
Money pick
Kevin McHughe
Spread pick
Jonah Black
Total pick
Simon Says
Spread pick
White Sox vs. Guardians: Williams' Strikeouts Meet Newcomb's 2.77 ERA
Analysis updated September 14, 2026 at 5:01 AM CDT
Cleveland gets a narrow winner lean behind Williams. That doesn't establish a worthwhile bet at SPF's price.
The probable starters shape the price
Gavin Williams' strikeout production is the strongest case for Cleveland at SPF's -149 moneyline against Chicago (+123). Sports statistics site StatMuse lists Williams and White Sox left-hander Sean Newcomb as the probable starters: Williams has 228 strikeouts in 169 innings, compared with Newcomb's 78 in 84⅓ innings.
Newcomb counters with a 2.77 ERA, below Williams' 3.78. Williams has sustained his strikeout production over roughly twice as many innings, but that larger workload doesn't establish how long either pitcher will last Monday. Cleveland is the narrow winner pick; the moneyline wager is Pass.
Availability matters for the total
StatMuse lists Cleveland's Rhys Hoskins on the 10-day injured list with a back injury and Chase DeLauter as day-to-day with a hamstring injury. Chicago's Tommy Pham is on the 10-day injured list with a calf injury. DeLauter's status leaves a lineup question unresolved.
SPF sets the total at 7, with over -102 and under -118. The pitchers' ERAs alone don't justify paying for the under without confirmed lineups and a clearer view of bullpen availability. Pass on the total.
Pick
Cleveland Guardians
Confidence
low
Betting lean
Pass