NFL Predictions

Seattle Seahawks vs Denver Broncos Predictions

Thursday, October 15, 2026 at 8:15pm EST at Empower Field at Mile High, Denver, CO

Seattle

Seahawks

Spread -2.5
@
Denver

Broncos

Spread +2.5
50% 50%
Spread Seattle Seahawks -2.5 Denver Broncos +2.5
Moneyline Seattle Seahawks -142 Denver Broncos +120
Total Over 40.5 (-112) Under 40.5 (-108)

Who wins this game?

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Seahawks vs. Broncos Prediction: Injury Questions Make Seattle’s Price Unappealing

Analysis updated October 14, 2026 at 7:29 AM CDT

Denver could be missing key defensive backs, but Seattle’s own availability questions make its -142 moneyline difficult to justify.

Denver’s secondary faces key injury questions

Seattle is a 2.5-point road favorite with a -142 moneyline, while Denver is +120. The clearest matchup concern favors the Seahawks: the Denver Broncos reported that cornerback Pat Surtain II and safety Talanoa Hufanga were estimated nonparticipants Tuesday for the second consecutive day. Cornerback Riley Moss was estimated limited for a second straight day.

Those absences could weaken Denver’s secondary, but final game designations aren’t available in the supplied evidence. That uncertainty makes it difficult to determine whether Seattle’s potential matchup advantage justifies the moneyline price.

Seattle also has unresolved availability

The Seattle Seahawks listed wide receiver Jaxon Smith-Njigba, quarterback Drew Lock, running back Zach Charbonnet and defensive tackle Leonard Williams as estimated limited participants Tuesday. Coach Mike Macdonald said Monday that Charbonnet was unlikely to return this week, although that could change. Linebackers Drake Thomas and Chazz Surratt were estimated nonparticipants.

No records, recent results, season statistics or confirmed starters are available to establish a separate football edge. Seattle is the likely winner because the SPF market favors it, but that alone isn’t a sound reason to lay -142 on the road.

Betting assessment

The 50-50 public split is a default figure, so it provides no betting signal. The total is 40.5, with the over at -112 and the under at -108, but the available evidence doesn’t support either side. Pass on the spread, moneyline and total.

Pick Seattle Seahawks
Confidence low
Betting lean Pass
Odds and availability can change. Confirm current markets before placing a wager.
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