Away
Houston Astros
Spread
+1.5
MLB Predictions
Houston Astros vs Cleveland Guardians
Wednesday, April 22, 2026 at 1:10pm EST
VS
Home
Cleveland Guardians
Spread
-1.5
56%
44%
Spread
Houston Astros +1.5
Cleveland Guardians -1.5
Moneyline
Houston Astros +139
Cleveland Guardians -168
Total
Over 8 (-112)
Under 8 (-108)
Professional Picks
7 listed
Professional Picks On This Game
Tom Strickland
Money pick
Hunter Meeks
Total pick
Vic Diamante
Money pick
Jonah Black
Total pick
Jimmy Wood
Total pick
Roger Kruzinski
Spread pick
Matt O'Brien
Money pick