MLB Predictions

Chicago White Sox vs Arizona Diamondbacks

Wednesday, April 22, 2026 at 9:40pm EST

Away

Chicago White Sox

Spread +1.5

Home

Spread -1.5

53%

47%

Spread Chicago White Sox +1.5 Arizona Diamondbacks -1.5

Moneyline Chicago White Sox +129 Arizona Diamondbacks -156

Total Over 9 (-112) Under 9 (-110)

Professional Picks

7 listed

Tom Strickland Total pick

In Progress

Rich Roth Spread pick

In Progress

Simon Says Spread pick

In Progress

Hunter Meeks Money pick

In Progress

Blake Mitchum Total pick

In Progress

Jonah Black Spread pick

In Progress

Jonah Black Total pick

In Progress

Previous Matchups

3/6 3/19 4/21 4/22 4/23