Away
Houston Astros
Spread
+1.5
MLB Predictions
Houston Astros vs Cleveland Guardians
Tuesday, April 21, 2026 at 6:10pm EST
VS
Home
Cleveland Guardians
Spread
-1.5
59%
41%
Spread
Houston Astros +1.5
Cleveland Guardians -1.5
Moneyline
Houston Astros +129
Cleveland Guardians -156
Total
Over 8.5 (-122)
Under 8.5 (+102)
Professional Picks
0 listed
Professional Picks On This Game
No professional picks are available for this matchup.