Florida State Seminoles vs Pittsburgh Panthers Predictions
Friday, November 13, 2026 at 7:00pm EST at Acrisure Stadium, Pittsburgh, PA
Panthers
Who wins this game?
Professional Picks On This Game
Florida State vs. Pittsburgh Prediction: QB Absence Makes Pitt a Pass
Analysis updated November 12, 2026 at 8:08 AM CST
Pitt is the likely winner at home, but the Panthers’ quarterback absence and Florida State’s 13 unavailable players make every SPF market difficult to price.
Injuries cloud Pitt’s market edge
Pittsburgh hosts Florida State on Friday, Nov. 13, at 7 p.m. ET as a 3.5-point favorite. SPF lists the Panthers at -170, the Seminoles at +142 and the total at 53.5.
ACC Sports Journal, which covers Atlantic Coast Conference football, reports that Pitt quarterback Mason Heintschel is out. Tight ends Elijah Lagg and Max Hunt, wide receivers Tyreek Robinson and Rodney Dunbar, linebacker Cameron Lindsey, and defensive backs Allen Bryant and Isaac Patterson are also out. Five more Panthers are questionable, including running back Ja'Kyrian Turner.
Florida State has 13 players out, according to the same report. The list includes running backs Samuel Singleton Jr., Quintrevion Wisner and Ousmane Kromah, wide receiver Duce Robinson, offensive lineman Bradyn Welch-Joiner and six defensive players. Those losses make Florida State difficult to back even with 3.5 points.
Betting view
Pitt is the likely winner because the SPF market favors the Panthers at home, but -170 is too expensive without evidence showing how the offense will function without Heintschel. The available information also doesn’t establish whether Pitt can cover 3.5 points or whether Florida State can take advantage of the quarterback absence.
The total is also a pass. With no season statistics, recent results or confirmed replacement lineups available, the injury report alone can’t support an Over or Under wager at 53.5. The listed 50-50 split is a default figure rather than sourced public-betting data, so it adds nothing to the decision.