NCAAF Predictions

Yale Bulldogs vs Pennsylvania Quakers Predictions

Friday, October 23, 2026 at 7:00pm EST at Franklin Field, Philadelphia, PA

Yale

Bulldogs

3-2
Spread -5.5
@
Pennsylvania

Quakers

Spread +5.5
50% 50%
Spread Yale Bulldogs -5.5 Pennsylvania Quakers +5.5
Moneyline Yale Bulldogs -198 Pennsylvania Quakers +157
Total Over 49.5 (-110) Under 49.5 (-113)
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Yale vs. Penn Prediction: Bulldogs Favored by 4.5

Analysis updated October 22, 2026 at 7:33 AM CDT

Hugo Djeumeni Kemeni leads Yale’s case at Franklin Field, while Penn’s productive pass rush could help the Quakers stay within one score.

Yale vs. Penn odds

Yale is a 4.5-point road favorite for Friday night’s game at Franklin Field. The Bulldogs are -175 on the moneyline, Penn is +140, and the total is 49.5. The over is -110 and the under is -113.

Can Penn slow Yale’s running game?

Yale University Athletics reports that Hugo Djeumeni Kemeni has rushed for 659 yards through five games, including 243 yards in last week’s 41-23 loss to Rhode Island. Yale finished that game with 289 rushing yards, giving the Bulldogs a clear way to control possession against Penn.

Penn has two defenders capable of disrupting that plan. Joey Holliday and Duncan McPherson have combined for seven sacks and nine tackles for loss. Negative plays from that pair could put Yale in longer passing situations and help Penn cover +4.5.

Penn needs better quarterback play

Penn lost 28-27 to Columbia after a potential winning field goal fell short. Quarterbacks Miles Teodecki and Karson Siqueiros-Lasky have combined for 1,207 passing yards, six touchdowns and eight interceptions. Those turnovers make Penn difficult to back even though Mason Page leads the team with 24 catches for 301 yards.

Prediction

Yale is 3-2 overall and 1-1 in Ivy League play, while Penn is 2-3 and 0-2. Kemeni’s production makes the Bulldogs the likelier winner, but probable starters and injury information aren’t available. That uncertainty rules out laying 4.5 points or paying -175 on the road. The pick is Yale to win, with no wager at the available prices.

Pick Yale Bulldogs
Confidence low
Betting lean Pass
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