MLB Predictions

Houston Astros vs Chicago Cubs

Friday, May 22, 2026 at 2:20pm EST

Away

Houston Astros

Spread +1.5

Home

Spread -1.5

51%

49%

Spread Houston Astros +1.5 Chicago Cubs -1.5

Moneyline Houston Astros +123 Chicago Cubs -148

Total Over 7 (+103) Under 7 (-124)

Professional Picks

2 listed

Diamond Ray James Money pick

In Progress

Roger Kruzinski Total pick

In Progress

Previous Matchups

5/22