Iowa State Cyclones vs Arizona Wildcats Predictions, Odds & Picks

Arizona is the likely winner, not a worthwhile bet

Arizona's -345 moneyline and 10.5-point spread make the Wildcats the clear market favorite at home. Arizona is the straight-up pick, but the price is too steep without season statistics, recent results or confirmed starters to measure the gap between these teams.

The same limitation applies to the 51.5 total. Without offensive, defensive or weather data, there is no sound basis for an over or under bet. Pass on the game.

Absences add risk to the spread

Yahoo Sports / USA TODAY Network reported that Iowa State will be without cornerback Benji Ngoyi, defensive ends Trey Verdon and Caden Crawford, and defensive tackles Donovan Fitzmaurice and Ka'Mori Moore. Those five absences leave the Cyclones missing four defensive linemen, but the available evidence does not show how effectively Iowa State can replace them.

Arizona will be without wide receivers Giovanni Richardson and Chris Hunter III, tight end Cole Rusk, offensive lineman Keona Peat, safety Dajon Hinton, cornerback Swayde Griffin and defensive lineman Ezra Funa, according to the same report. Safety Lee Molette III was removed from the availability report. Arizona's losses among its pass catchers and offensive line add uncertainty to a wager that requires the Wildcats to win by at least 11 points.

Pick Arizona Wildcats

Confidence low

Betting lean Pass

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Iowa State Cyclones vs Arizona Wildcats Predictions

Cyclones

Wildcats

Professional Picks On This Game

Iowa State vs. Arizona Prediction: Wildcats Favored, but Pass at -10.5

Arizona is the likely winner, not a worthwhile bet

Absences add risk to the spread