Pittsburgh Pirates vs Chicago White Sox Predictions
Thursday, September 10, 2026 at 7:40pm EST at Rate Field, Chicago, Illinois
White Sox
75-70Who wins this game?
Professional Picks On This Game
Pirates vs. White Sox prediction: Smith gives Chicago a slight edge
Analysis updated September 10, 2026 at 5:06 AM CDT
Chicago's probable starter has a 0.56 ERA, but Pittsburgh arrives hitting .279 over its last 10 games. SPF lists both teams at -110.
Smith faces a hot Pittsburgh lineup
Hagen Smith gives Chicago the strongest argument at SPF's matching -110 moneylines. StatMuse / Associated Press, which carries the AP matchup preview, lists the left-hander as the probable starter with a 0.56 ERA and 0.94 WHIP. Pittsburgh's probable starter, Jared Jones, has a 4.46 ERA and 1.23 WHIP. Those numbers favor Smith, though his innings total isn't provided, limiting how much weight to put on the gap.
Pittsburgh has gone 8-2 with a .279 batting average over its last 10 games, according to the same preview. Chicago is 3-7 and hitting .205 in that span. The Pirates' recent hitting makes backing Smith less straightforward than the ERA comparison suggests.
Chicago's 43-30 home record tips my winner pick narrowly toward the White Sox. But -110 requires a win rate above 52.4% to break even, and the pitching comparison and recent form don't establish that edge clearly enough. The moneyline is a pass.