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Scores and Odds for 9/21/2025
Below are the scores, odds and scores (if applicable) of the games on 9/21/2025. Want today's winners? Purchase premium sports picks.
MLB Scores and Odds
| Final | SP | OU | Score |
| Oakland | +1.5 | 8.5 | 0 |
| Pittsburgh | -1.5 | Over | 11 |
| Final | SP | OU | Score |
| Chicago | +1.5 | 9 | 0 |
| Cincinnati | +1.5 | Under | 1 |
| Final | SP | OU | Score |
| Washington | +1.5 | 8.5 | 3 |
| New York | -1.5 | Under | 2 |
| Final | SP | OU | Score |
| Toronto | -1.5 | 8.5 | 8 |
| Kansas City | +1.5 | Over | 5 |
| Final | SP | OU | Score |
| Los Angeles | -1.5 | 11.5 | 1 |
| Colorado | +1.5 | Under | 3 |
| Final | SP | OU | Score |
| Philadelphia | -1.5 | 8.5 | 2 |
| Arizona | +1.5 | Over | 9 |
| Final | SP | OU | Score |
| San Francisco | +1.5 | 9.5 | 3 |
| Los Angeles | -1.5 | Under | 1 |
NFL Scores and Odds
| Final | SP | OU | Score |
| Cincinnati | +3.5 | 43.5 | 10 |
| Minnesota | -3 | Over | 48 |
| Final | SP | OU | Score |
| Houston | +1.5 | 43 | 10 |
| Jacksonville | -1 | Under | 17 |
| Final | SP | OU | Score |
| Indianapolis | -6 | 43 | 41 |
| Tennessee | +6.5 | Over | 20 |
| Final | SP | OU | Score |
| Las Vegas | +2.5 | 44 | 24 |
| Washington | -1.5 | Over | 41 |
| Final | SP | OU | Score |
| Los Angeles | +4 | 44.5 | 26 |
| Philadelphia | -3.5 | Over | 33 |
| Final | SP | OU | Score |
| Pittsburgh | +1 | 44 | 21 |
| New England | +1.5 | Under | 14 |
| Final | SP | OU | Score |
| Denver | +2.5 | 45.5 | 20 |
| Los Angeles | -1.5 | Under | 23 |
| Final | SP | OU | Score |
| New Orleans | +7 | 42 | 13 |
| Seattle | -6.5 | Over | 44 |
| Final | SP | OU | Score |
| Arizona | +1.5 | 44 | 15 |
| San Francisco | -1.5 | Under | 16 |
| Final | SP | OU | Score |
| Kansas City | -6 | 44.5 | 22 |
| New York | +6.5 | Under | 9 |
NCAAF Scores and Odds
| Final | SP | OU | Score |
| Fresno State | -3.5 | 46.5 | 23 |
| Hawaii | +3.5 | Under | 21 |
