NFL Predictions

San Francisco 49ers vs Philadelphia Eagles

Sunday, January 11, 2026 at 4:30pm EST

Away

San Francisco 49ers

Spread +5.5

Home

Spread -5.5

52%

48%

Spread San Francisco 49ers +5.5 Philadelphia Eagles -5.5

Moneyline San Francisco 49ers +205 Philadelphia Eagles -250

Total Over 44.5 (-110) Under 44.5 (-110)

Professional Picks

3 listed

Tom Strickland Spread pick

In Progress

Simon Says Spread pick

In Progress

Matt O'Brien Total pick

In Progress

Previous Matchups

1/11