vs
Game Date:
09/28/2025
4:05pm EST
Lines:
Indianapolis Colts +3.5
Los Angeles Rams -3.5
Total:
Over
49.5 (-105)
Under 49.5 (-115)
Community Picks: Indianapolis Colts 61% vs Los Angeles Rams 39%
Indianapolis Colts and Los Angeles Rams Thread
Previous Matchups: 9/28
