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Scores and Odds for 9/22/2021
Below are the scores, odds and scores (if applicable) of the games on 9/22/2021. Want today's winners? Purchase premium sports picks.
MLB Scores and Odds
| Closed | SP | OU | Score |
| Pittsburgh | +1.5 | 8.5 | 0 |
| Cincinnati | -1.5 | 0 |
| Open | SP | OU | Score |
| Chi White Sox | -1.5 | 9 | 0 |
| Detroit | +1.5 | 0 |
| Open | SP | OU | Score |
| Kansas City | +1.5 | 8.5 | 0 |
| Cleveland | -1.5 | 0 |
| Final | SP | OU | Score |
| Washington | +1.5 | 8 | 7 |
| Miami | -1.5 | Over | 5 |
| Final | SP | OU | Score |
| Baltimore | +1.5 | 8 | 3 |
| Philadelphia | -1.5 | Under | 4 |
| Final | SP | OU | Score |
| Texas | +1.5 | 9 | 3 |
| NY Yankees | -1.5 | Over | 7 |
| Final | SP | OU | Score |
| LA Dodgers | -1.5 | 10.5 | 5 |
| Colorado | +1.5 | Over | 10 |
| Final | SP | OU | Score |
| San Francisco | -1.5 | 9.5 | 8 |
| San Diego | +1.5 | Over | 6 |
MLS Scores and Odds
| Closed | SP | OU | Score |
| Inter Miami CF | 2.25 | 0 | |
| Nashville SC | 0 |
| Closed | SP | OU | Score |
| Chicago Fire FC | 2.75 | 0 | |
| New England Revolution | 0 |
| Closed | SP | OU | Score |
| New York Red Bulls | 2.5 | 0 | |
| New York City FC | 0 |
