NFL Predictions

New England Patriots vs Buffalo Bills

Sunday, October 5, 2025 at 8:20pm EST

Away

New England Patriots

Spread +7.5
VS
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Buffalo Bills

Spread -7.5
53%
47%
Spread New England Patriots +7.5 Buffalo Bills -7.5
Moneyline New England Patriots +320 Buffalo Bills -425
Total Over 48.5 (-120) Under 48.5 (+100)
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