NCAAF Predictions

Virginia Cavaliers vs Louisville Cardinals

Saturday, October 4, 2025 at 3:30pm EST

Away

Virginia Cavaliers

Spread +6.5

Home

Spread -6.5

54%

46%

Spread Virginia Cavaliers +6.5 Louisville Cardinals -6.5

Moneyline Virginia Cavaliers +180 Louisville Cardinals -215

Total Over 60.5 (-110) Under 60.5 (-110)

Professional Picks

0 listed

No professional picks are available for this matchup.