Away
San Francisco 49ers
Spread
+8.5
NFL Predictions
San Francisco 49ers vs Los Angeles Rams
Thursday, October 2, 2025 at 8:15pm EST
VS
Home
Los Angeles Rams
Spread
-8.5
56%
44%
Spread
San Francisco 49ers +8.5
Los Angeles Rams -8.5
Moneyline
San Francisco 49ers +340
Los Angeles Rams -450
Total
Over 43.5 (-105)
Under 43.5 (+100)
Professional Picks
6 listed
Professional Picks On This Game
Tom Strickland
Spread pick
Tom Strickland
Total pick
Simon Says
Total pick
Matt O'Brien
Total pick
Wes Salvato
Spread pick
Wes Salvato
Total pick