NFL Predictions

New Orleans Saints vs Buffalo Bills

Sunday, September 28, 2025 at 1:00pm EST

Away

New Orleans Saints

Spread +15.5

Home

Spread -15.5

52%

48%

Spread New Orleans Saints +15.5 Buffalo Bills -15.5

Moneyline New Orleans Saints +900 Buffalo Bills -1800

Total Over 48.5 (-115) Under 48.5 (-105)

Professional Picks

2 listed

Tom Strickland Spread pick

In Progress

Wes Salvato Spread pick

In Progress