NCAAF Predictions

Louisville Cardinals vs Pittsburgh Panthers

Saturday, September 27, 2025 at 12:00pm EST

Away

Louisville Cardinals

Spread -3.5

Home

Spread +3.5

47%

53%

Spread Louisville Cardinals -3.5 Pittsburgh Panthers +3.5

Moneyline Louisville Cardinals -165 Pittsburgh Panthers +140

Total Over 53.5 (-120) Under 53.5 (+100)

Professional Picks

1 listed

Simon Says Spread pick

In Progress