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Jacksonville Jaguars
vs
San Francisco 49ers
Today's Featured Sports Pick

Game Date:
09/28/2025
4:05pm EST

Lines:
Jacksonville Jaguars +3.5
San Francisco 49ers -3.5

Total:
Over 46.5 (-105)
Under 46.5 (-115)

Community Picks: Jacksonville Jaguars 52% vs San Francisco 49ers 48%

Jacksonville Jaguars and San Francisco 49ers Thread

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Previous Matchups: 9/28
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