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New Orleans Saints
vs
Buffalo Bills
Today's Featured Sports Pick

Game Date:
09/28/2025
1:00pm EST

Lines:
New Orleans Saints +15.5
Buffalo Bills -15.5

Total:
Over 48.5 (-115)
Under 48.5 (-105)

Community Picks: New Orleans Saints 52% vs Buffalo Bills 48%

New Orleans Saints and Buffalo Bills Thread

Team Tweets & News Articles
 
Previous Matchups: 9/28
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