MLB Predictions

Pittsburgh Pirates vs St. Louis Cardinals

Thursday, May 21, 2026 at 1:15pm EST

Away

Pittsburgh Pirates

Spread -1.5

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Spread +1.5

Spread Pittsburgh Pirates -1.5 St. Louis Cardinals +1.5

Moneyline Pittsburgh Pirates -126 St. Louis Cardinals +104

Total Over 8 (-102) Under 8 (-118)

Professional Picks

7 available

Rich Roth Spread pick

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Mike Millen Spread pick

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Blake Mitchum Total pick

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John Thompson Spread pick

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Diamond Ray James Spread pick

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Diamond Ray James Total pick

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Vic Diamante Spread pick

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Previous Matchups

3/1 3/5 4/27 4/28 4/29 4/30 5/19 5/20 5/21