MLB Predictions

New York Yankees vs Boston Red Sox Predictions

Tuesday, April 21, 2026 at 6:45pm EST

Away

New York Yankees

Spread -1.5

Home

Spread +1.5

Bet Signal No verified split available · 50/50 default

50%

Spread New York Yankees -1.5 Boston Red Sox +1.5

Moneyline New York Yankees +100 Boston Red Sox -121

Total Over 8.5 (-105) Under 8.5 (-115)

Professional Picks

5 listed

Tom Strickland Total pick

In Progress

Joe Napoli Total pick

In Progress

Vic Diamante Total pick

In Progress

Jimmy Wood Total pick

In Progress

Abe Howland Total pick

In Progress

Previous Matchups

3/4 3/18 4/21 4/22 4/23 6/5 6/6 6/7 6/25 6/26 6/27 6/28 8/28 8/29 8/29 8/30