NFL Predictions

Buffalo Bills vs Cleveland Browns

Sunday, December 21, 2025 at 1:00pm EST

Away

Buffalo Bills

Spread -10.5

Home

Spread +10.5

43%

57%

Spread Buffalo Bills -10.5 Cleveland Browns +10.5

Moneyline Buffalo Bills -600 Cleveland Browns +440

Total Over 41.5 (-108) Under 41.5 (-112)

Professional Picks

2 listed

Tom Strickland Total pick

In Progress

Matt O'Brien Spread pick

In Progress